FILTERON  (FILTERON)  tablet

Ingredients (in 1 tablet)
Active ingredients: 
Soy lecithin phospholipids (La-lecithin) ………..… 200 mg
L-Glutathione ………………………………………….. 200 mg
Ademetionine …………………...………………… 100 mg
Vitamin E (Tocopherol) ………………………..…… 15 mg

Excipients: microcrystalline cellulose, potato starch, silicon dioxide, magnesium stearate. 

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Product Information 
Filteron is used in the complex treatment of various liver diseases based on the properties, biological activity and specific mechanism of action of the components contained in it.  
Soy lecithin phospholipids (La-lecithin) is a complex of phospholipids (phosphatidylcholine, phosphatidylserine and phosphatidylinositol) contained in soybean lecithin. Irreplaceable phospholipids are components of the cell membrane of hepatocytes and are important for its synthesis, stability and regeneration of biological structures. During various diseases of the liver, lecithin reduces the cytotoxic effect of lymphocytes and necrosis of hepatocytes. Irreplaceable phospholipids regulate the functioning of cellular mechanisms: ion exchange, tissue respiration, biological oxidation, activity of respiratory enzymes in mitochondria, energy metabolism of cells; normalizes disturbed lipid metabolism. It normalizes protein and fat metabolism, has a lipotropic effect, protects the cellular structure of the liver, restores the immune functions of lymphocytes and macrophages. 
L-glutathione is a combination of a tripeptide consisting of L-glutamine, glycine and L-cysteine with a sulfhydryl group. Being a strong antioxidant, it plays an important role in protecting the cells of the body. By combining with xenobiotics and their toxic metabolites, it increases their hydrophilicity and reduces their toxicity. It reduces organic peroxides to alcohols and binds free radicals. By combining with many lipophilic compounds, it prevents them from penetrating through the membranes and disrupting the function of the cell (physical neutralization). As a result, it improves the stability of the cell membrane, protects the cell membrane, increases the activity of liver enzymes, strengthens the detoxification and regeneration activity of the liver by inactivating free radicals. 
The neutralization system with the participation of glutathione is the most important defense mechanism of the cell and plays a unique role in the formation of the body's resistance to various influences. Its combinations with xenobiotics are more hydrophilic, less toxic and more easily removed from the body. 
Ademetionine (S-adenosyl-L-methionine) is a hepatoprotector. It has a choleretic and cholekinetic effect. It has detoxification, regenerating, antioxidant, antifibrotic, neuroprotective and antidepressant properties. Participates in biological transmethylation reactions – is a methyl group donor for participation in methylation reactions of cell membrane phospholipids, proteins, hormones, neurotransmitters; As a precursor of cysteine, taurine, glutathione (which provides the oxidation-recovery mechanism of cellular detoxification), it participates in transsulfation reactions, coenzyme acetylation. Increases the level of glutamine in the liver, cysteine and taurine in the plasma; by normalizing metabolic reactions in the liver, it reduces the level of methionine in the plasma. In addition to the decarboxylation process, putrescine (stimulator of hepatocyte proliferation and cell regeneration), which is included in the structure of ribosomes, participates in aminopropylation processes as a precursor of polyamines such as spermidine and spermine. 
It has a choleretic effect: it increases membrane mobility and polarization by stimulating the synthesis of phosphatidylcholine in hepatocytes. As a result, it improves the function of the transport system of bile acids in connection with the membrane of hepatocytes and the passage of bile acids to the bile ducts. It is effective during internal cholestasis (disturbance of bile synthesis and flow). It detoxifies bile acids, increases the amount of combined and sulfated bile acids in hepatocytes. As a result of its combination with taurine, the dissolution of uric acids and their removal from the hepatocyte increases. The process of sulfation of bile acids allows them to be excreted by the kidneys, pass through the membrane of the hepatocyte and be excreted in the bile. In addition, sulfated bile acids protect the membrane of hepatocytes from the toxic effect of unsulfated bile acids (accumulated in large quantities in hepatocytes during intrahepatic cholestasis). In patients with diffuse diseases with intrahepatic cholestasis syndrome (cirrhosis, hepatitis)   it reduces skin itching and the level of biochemical indicators (o c. straight bilirubin, alkaline phosphatase activity, aminotransferases). 
Vitamin E is an important component of the body's antioxidant defense system, preventing the formation of free radicals that damage cell membranes. It acts as a cofactor of several enzyme systems. It inhibits the oxidation of unsaturated fatty acids. It participates in the biosynthesis of heme and proteins, cell proliferation, tissue respiration and other important processes of tissue metabolism, prevents the hemolysis of erythrocytes, prevents the increase of permeability and fragility of capillaries, stimulates the synthesis of protein and collagen. Vitamin E has a therapeutic effect in liver diseases: it reduces the risk of oxidative stress and steatosis during non-alcoholic fatty liver disease. 

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Scope and main instructions:  .
It is prescribed in the complex treatment of the following diseases:
-    Hepatic fibrosis, fatty dystrophy of the liver 
-    Non-alcoholic fatty liver disease
-    Intrahepatic cholestasis in acute and chronic hepatitis, cirrhosis and pre-cirrhotic cases
-     Liver with various etiologies, that c. toxic injuries caused by alcohol, radiation, viruses, drugs (antibiotics, tumor -, virus -, anti-tuberculosis drugs, tricyclic antidepressants, oral contraceptives)
-    Chronic noncalculous cholecystitis, cholangitis
-     Hepatic encephalopathy, coma
-     Food and drug poisoning
-    Sclerotic lesions of vessels
-    Abstinence syndrome
-    Depression
-     In order to reduce the hepatotoxic effects of anticonvulsant, psychotropic, hormonal drugs
-    Chemical therapy to reduce hepatotoxicity in the treatment of gout 
-    General healing, antiaging therapy

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Contraindications: Hypersensitivity to any component contained in the product.

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Instructions for use and dosage: Adults: 1 tablet once a day.

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Side effects: Not observed.

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Interaction with other drugs: Not known.

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Toxicology: The amount of components in the product is safe.

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Special precautions: Do not exceed the recommended daily dose. BFMGA does not replace normal nutrition. It cannot be used for the purpose of treating diseases. Consult a doctor during pregnancy and lactation, illness or medication use. 

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Release form: Tablet No. 30, in a blister. 2 blisters (2x15) are packed in a cardboard box with a leaflet.

 

Storage conditions: should be stored at a temperature not higher than 25°C, cool, dry, away from direct sunlight and out of the reach of children.

 

Shelf life: 3 years. Do not use after the expiration date.

 

Manufacturer: Pharmacy Laboratories sc, Poland.